Our apartment has the best location. Duomo in 10 mins, Central station in 3 mins by metro just downstairs (LORETO Cross line MM1&MM2). Cross the street you are in the most popular commercial street Corso Buenos Aires, how should we say...where you can find 2 McDonald's in 3 minutes.
Although it's in very center of Milan, the apartment itself is incredibly quiet. The building is sitting behind a courtyard, having a tea in its super bright balcony you wouldn't hear any noise from street.